Items where Subject is "Physiology"
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Acid base balance (BM4)
Slides accompanying lecture covering: pH, acids, bases and buffers; handling acids and bases; control of acid base balance in the lungs and kidneys; metabolic acidosis
Acid base tutorial
Question sheet accompanying acid base tutorial for the Respiratory, Cardiovascular and Renal 2 module
Acromegaly case and commentary
Case study accompanying lectures on growth hormone and pituitary gland
Acute kidney injury and case study
Slides accompanying lecture on the pathophysiology of acute kidney injury, covering: functions of the kidney; anatomy of the kidney; filtration, reabsorption and secretion; the nephron and key hormones; the pathophysiology and clinical aspects of AKI
Anaemia - part 1
Slides accompanying first lecture on anaemia, covering: the physiology of red cell production and breakdown, haemoglobin, and iron, B12 and folate metabolism; microcyctic anaemia (iron deficiency and thalassaemia); macrocytic anaemia (B12 deficiency)
Arrhythmias
Slides accompanying session on arrhythmias, covering: mechanisms of arrhythmogenesis; consequences of arrhythmias; classification of heart rhythms
Assessing the critically ill or injured patient
An explanation of how to recognise a critically ill patient, and a structured approach to assessing and treating such a patient
Asthma: an overview of pathophysiology and treatment
Slides accompanying symposium on asthma, looking at the abnormal airway physiology and pathology underlying asthma, and its clinical presentation, epidemiology and treatment
Autoregulation of cerebral blood flow
Slides accompanying lecture on autoregulation and treating raised ICP
Biliary tree and pancreas
Slides accompanying lecture covering: bile; bilirubin; bile flow; function of bile acids; pancreas and pancreatic secretion
Blood gas maintenance and acid-base balance (BM4)
Slides accompanying lecture covering: respiratory failure; interpretation of blood gases; V/Q mismatch; acid base balance
Blood pressure
Measurement and monitoring of blood pressure. Clinical skills lecture by Claire Townsend 2019
Body Fluids 1
The full powerpoint from Prof SHelley Parrs lecture on Body Fluids 1. Please remember not to look ahead before watching videos or it will defeat the purpose of the exercises.
Body Fluids 2
Full Powerpoint for session Please do not look ahead before watching videos or it will defeat the purpose of the exercises
Brain Homeostasis & ICP
Slides accompanying online lecture (BM5 Year 2 Nervous system module MEDI2046)
Breast feeding and infant nutrition - Part 1 Breast feeding
Slides accompanying symposium on the breast and lactation, covering: mammary gland anatomy and development; hormonal control of milk production; stimulation of milk secretion; milk components; weaning; breast complications; pharmacological intervention of lactation
Burns 1: introduction and the pathophysiology of burns and burns shock
Slides accompanying SBoM on burns
Calcium homeostasis
Slides accompanying lecture exploring how calcium homeostasis is maintained, the disorders resulting from loss of calcium homeostasis and the skeletal changes occurring in rickets/osteomalacia
Cardiac action potential and cardiac muscle
Slides accompanying lecture on cardiac action potential and cardiac muscle
Cardiac function
Slides accompanying lecture covering: the cardiac cycle; what determines cardiac output; the physiology behind ECGs
Cardiopulmonary responses to exercise
Slides accompanying lecture, covering: definitions of exercise and its clinical importance; dynamic exercise; exercise tesing
Cardiorespiratory physiology and pathophysiology
Slides accompanying lecture on applied physiology on the ICU
Cardiovascular examination for Beginners
Introduction to clinical examination and the construction of how to elicit a history and perform a clinical examination of the cardiovascular system
Catabolic hormones
Slides accompanying session on the anabolic and catabolic control of metabolism, focusing on glucagon, and glucose homeostasis.
Cell to cell communication 2 lecture handout
The powerpoint file used to deliver this lecture via recorded videos
Central and peripheral nervous systems histology and physiology
Slides accompanying session covering: cell types and roles within the CNS and PNS; neuronal transmission within the CNS and PNS
Chronic Pain Symposium
Slides accompanying symposium on chronic pain, covering: the effects of living with chronic pain; the role of pain management clinics; treatment options available
Clinical aspects of the autonomic nervous system
Lecture slides accompanying session relating the physiology and dysfunction of the autonomic nervous system (ANS) with clinical conditions
Clinical physiology in the seriously injured patient
Slides accompanying lecture on major trauma, covering the causes of major trauma, the structured approach, catastrophic haemorrhage, case studies and accident prevention.
Colon, rectum and anus
Slides accompanying lecture covering: functions of large intestine; ileo caecal valve; colon movements; ion and water transport in the colon; defaecation
Diabetic ketoacidosis
Slides accompanying lecture on diabetic ketoacidosis, covering the clinical aspects; hyperglycemia, ketosis and acidosis; and the physiology of treatment
Diabetic nephropathy
Slides accompanying lecture covering: the pathophysiology of diabetic nephropathy; the extent of the problem and how it can be managed
Diabetic retinopathy: clinical features, pathophysiology and treatment
Slides in three parts, accompanying lecture on diabetic retinopathy. 1. Clinical features and classification of diabetic retinopathy 2. How does diabetes cause retinopathy? Pathophysiology of diabetic retinopathy 3. Management of diabetic retinopathy
Dialysis
Slides accompanying lecture covering: functions of the kidney; principles of dialysis; renal replacement therapy
Digestion and absorption
Slides accompanying lecture covering: principles of digestion and absorption; how these are regulated; digestion and absorption of specific nutrients; malabsorption
Digestion and absorption
Slides accompanying lecture covering: digestion of protein, carbohydrate and fats; control of salt and water transport; diarrhoea; G proteins; cholera
Endocrine control of the menstrual cycle
Slides accompanying lecture covering: functions of the menstrual cycle; timeline of female reproductive function; hormonal contraception
Endocrine functions of the kidney
Slides accompanying lecture covering: erythropoiesis and erythropoietin; Ca2+ metabolism and vitamin D; blood pressure regulation and RAS
Equilibrium potentials - extra examples
Calculations relating to second session on physiology of ion distribution
Fluid volume and regulation
Lecture slides to accompany the lecture on fluid volume and its regulation
Functions of articular and growth plate cartilage
Slides accompanying session on the physiology of bone
Gas pressures and haemoglobin
Slides accompanying lecture on the physical properties of gases, and the structure and function of haemoglobin
Glomerular function
Slides accompanying lecture covering: recap of kidney function and renal blood flow; the glomerular filter; glomerular filtration
Glucose homeostasis
Slides accompanying lecture covering: the mechanism for maintaining glucose homeostasis and its relationship with lipid metabolism and insulin resistance; the physiological changes in diabetic ketoacidosis; how glucose is taken up into cells
Growing a baby: Fetal growth, maternal adaptations (sections by Dr Poore)
Slides accompanying 'Growing a baby' symposium, covering: maternal adaptations to pregnancy, fetal growth and its regulation; measuring fetal growth and its significance
Heart failure
Slides accompanying session looking at the anatomy and physiology of heart failure, its clinical presentation and management.
Hypothalamus and pituitary
Lecture slides covering the hypothalamus and pituitary, and growth hormone
Infant nutrition
Slides accompanying symposium on breast feeding and lactation, covering: issues of neonatal physiology; macronutrients and micronutrients of breast milk; advantages and contraindications for breast feeding; complementary feeding
Insulin
Slides accompanying lecture covering: glucose and its metabolism; blood glucose homeostasis; basic facts about insulin; insulin actions
Intrinsic Renal Diseases
Slides accompanying lecture covering: the glomerulus and proteinuria; nephrotic syndrome; diabetic nephropathy; haemolytic uraemic syndromw
Introduction to Pain Week
Contains 1. Overview of the field 2. Case (video) 3. Supporting information for the case 4. Resources for the supporting information a. Sciatica Option Grid b. NICE neuropathic pain pathway c. Startback d. Pain Management Programmes information 5. REsources for introductory lecture a.CMO England report on Pain
Introduction to visual pathways
Slides accompanying lecture covering: the visual pathway from retina to V1; visual defects associated with lesions along this pathway; pathways from V1 to other cortical regions
Ion Distribution 2
A copy of the powerpoint file used to make these recordings (minus some of the answers to the exercises). As ever please don't look ahead or it might ruin the exercises I encourage you to do.
Ionotropic Receptors
Lecture introducing the main concepts of ionotropic receptors in the central nervous system
Liver
Slides accompanying lecture describing the functions of the liver, covering: lipid and protein metabolism; the secretion and excretion of bilirubin; the metabolism of drugs
Liver physiology and clinical features
Slides accompanying symposium on liver disease, describing the physiology of the liver, and clinical features of liver disease
Lung mechanics and the carriage of oxygen
Slides accompanying lecture covering: gas pressures and partial pressure; an overview of lung mechanics; oxygen carriage and delivery
Mechanisms of acute neurodegeneration
Slides accompanying lecture covering: ischaemic neurodegeneration; the ischaemic core and ischaemic penumbra; clinical treatment for stroke patients
Metabolic Syndrome Symposium - Introduction
Metabolic Syndrome Symposium - Introduction by Dr Wootton
Metabolic Syndrome Symposium - Weight Management
Metabolic Syndrome Symposium - Weight Management slides by Steve Wooton
Metabolic basis of diabetes
Slides accompanying lecture covering: diabetes and metabolism; biochemistry and treatment of diabetes; the metabolic basis of clinical problems in diabetes, including hyperglycemia, dehydration, hypertriglyceridemia, hypoglycemia
Modifications to oxygen transport and carriage of carbon dioxide
Slides accompanying lecture covering disruption in oxygen carriage and the carriage of carbon dioxide and nitrogen
Motor control
Slides accompanying lecture covering: the role of reflexes in control of movement and the systems that integrate them into a co-ordinated motor control system; the central mechanisms involved in the generation of voluntary movements
Mouth, stomach and secretion
Combined slides accompanying lectures covering: saliva; swallowing; functions of the stomach; vomiting; pancreatic secretion
Nervous system - basic definitions and information
Preparatory handout for ANS physiology lectures - please read before the lectures
Normal birth
Slides accompanying lecture outlining the physiology of normal birth, and explaining how midwives facilitate normal birth and create a positive birth experience
Oxygen carriage and delivery to tissues
Slides accompanying lecture on haemoglobin and oxygen interactions, and haemoglobin and oxygen affinity.
Pain physiology
Slides accompanying lecture on the physiology of pain, describing the three main levels of processing involved in detection, transmission and response to pain.
Pathophysiology Part A (Oedema)
The powerpoint files that were used to create this video - please note there are exercises to undertake so please don't look ahead at slides until you have watched the video
Pathophysiology Part B (Oedema)
Powerpoint slides to accompany the second part of this session delivered by Dr Moutasim
Pathophysiology of acute kidney injury
Slides accompanying lecture on acute kidney injury including pre-renal, intra-renal and post-renal injury, and describing some example cases
Physiological Numeracy
This is a description of some basic physiological calculations based on the Fick Principle.
Physiological adaptations at birth
Slides accompanying lecture covering: birth; intrauterine life; foetal and neonatal circulation; the first breath; renal and other systems; jaundice and neonatal resuscitation
Physiology and pathology of ageing
Slides accompanying lecture on the physiology of ageing and consequences of the physiological changes with ageing
Physiology and pharmacology of labour
Slides accompanying lecture discussing: the process of labour; control of uterine activity; how the fetus matures in readiness for life after birth; pain relief during labour
Physiology in chronic kidney disease (CKD)
Slides accompanying renal physiology recap covering physiology in CKD
Physiology of Pain and Chronic Pain
Slides accompanying lecture covering the peripheral and central mechanisms involved in the detection, transmission and response to pain
Physiology of adrenal
Slides accompanying session covering: anatomy and overview of the adrenal function; regulation of adrenal output; actions of adrenal products; disorders of adrenal function
Physiology of ageing
Slides accompanying Ageing and Dementia SBoM, looking at the physiology of ageing and the consequences of physiological changes with ageing
Physiology of body fluids I
Lecture slides accompanying session, covering: introduction to Physiology in the Faculty; components of body fluids; disruption of body fluids
Physiology of body fluids II
Lecture slides accompanying session, covering: an overview of the composition of body fluids and how they are measured; the movement of fluids between compartments and cells of the body
Physiology of ion distribution I
Lecture slides accompanying session introducing cellular transport mechanisms, both active and passive.
Physiology of ion distribution II
Lecture slides accompanying session on the physiological basis of membrane potentials and action potentials
Physiology of shock
Slides accompanying lecture on shock, covering: osmotic forces; blood pressure regulation; the physiological responses to shock
Physiology of smooth muscle
Lecture slides accompanying session on the physiology of smooth muscle, covering muscle structure and mechanisms and control of contraction
Physiology of the autonomic nervous system
Lecture slides accompanying session introducing the basic physiology of the autonomic nervous system (ANS)
Physiology of the autonomic nervous system
Slides accompanying lecture covering: the divisions of the ANS; neurotransmitters and receptors; actions of the ANS; interactions of the SNS and PSNS; central nervous involvement; micturition
Physiology tutorial - renal clearances
Question sheet accompanying physiology tutorial on renal clearances
Placental anatomy and function
Slides accompanying lecture covering: what the placenta does; placental structure at term; placental development; how the placenta functions as a barrier; how nutrients are transported across the placental barrier; how placental hormones change maternal physiology
Placental function
Slides accompanying 'growing a baby' symposium, discussing the role of the placenta; placental development and structure; placental function as a nutrient transporter and as a barrier
Positive Inotropes (and Vasopressors)
A lecture to introduce some of the commoner drugs used clinically to manipulate the cardiovascular system and their mode of action
Protein handling in the kidney
Slides accompanying lecture covering: glomerular filtration; protein handling; types of proteinuria; testing for protein in the urine
Proximal tubule and loop of Henle function
Slides accompanying lecture giving an overview of the renal tubular function, and focusing on two regions of the nephron: the proximal convoluted tubule and the loop of Henle.
Pulmonary function tests
Slides accompanying lecture on the physiological basis of lung function tests
Renal blood flow
Slides accompanying lecture on renal blood flow, covering: introduction to renal function; blood flow to the kidney; blood flow in the kidney
Renal clearances
Slides accompanying lecture on renal clearances, covering: renal clearance as a measure of GFR; renal clearance as a measure of renal plasma flow
Renal clearances - additional examples
Additional questions accompanying physiology tutorial on renal clearances
Renal physiology 1 - glomerular function
Slides accompanying lecture covering: functions of the kidney; the renal filter; GFR and net filtration pressure; regulation of GFR
Renal physiology 2 - renal tubular function
Slides accompanying lecture covering: reabsorption and secretion; transport within cells; hormonal control; diuretic action
Renal physiology day - part 1
Slides accompanying lecture reviewing: functions of the kidney; renal anatomy; glomerular filtration; tubular reabsorption; tubular secretion; countercurrent multiplier; urinary concentration
Respiratory adaptation
Slides accompanying session on respiratory adaptation in response to exercise, illness, altitude or depth
Respiratory failure, oxygen therapy and blood gas interpretation
Slides accompanying lecture covering: basic respiratory physiology; respiratory failure in biochemical and clinical terms; oxygen therapy; approach to blood gas interpretation
Science to Practice: Neurology "Where is the lesion?"
Slides accompanying the lecture given by Dr Aravinthan Varatharaj 2019
Shock
Slides accompanying lecture on aspects of shock, including: causes; pathological changes; physiological mechanisms; inotropic drugs; disorders of acid-base balance; antimicrobial therapy
Skin deep
Lecture slides accompanying symposium on skin, exploring how physiology, histology and sociology are vital for a complete understanding of the structure and function of skin alongside living with the consequences of skin conditions
Sodium and potassium balance
Slides accompanying lecture covering: sodium handling in the nephron; potassium handling in the nephron; regulation of sodium and potassium; sodium and potassium balance
Somatosensory system and reflexes
Slides accompanying lecture covering: the sense organs in the periphery and their connection to the CNS; the co-localisation of sensory and motor pathways in the spinal cord; the functional integration of sensory and motor pathways in spinal reflexes
Spirometry
Handout explaining the procedures and equipment involved in measuring lung volumes and the volumes of gas moved during inspiration or expiration
Synaptic plasticity
Slides accompanying lecture covering: structure of CNS synapses; model organisms for studying synaptic plasticity; long-term potentiation; long-term depression
Synaptic transmission
Slides accompanying lecture covering: the basic concepts underlying synaptic transmission; how synaptic transmission may be regulated; the role of synaptic transmission in the CNS
The cardiac cycle
Slides accompanying lecture detailing changes in aortic pressure, left ventricular pressure, ventricular volume, heart sounds and atrial pulse during the cardiac cycle
The electrocardiogram (ECG) - practical
Handout accompanying cardiovascular physiology practical on the electrocardiogram (ECG)
The indirect measurement of blood pressure
Handout accompanying cardiovascular physiology practical on the measurement of blood pressure
The neurological examination
Slides describing how to carry out a neurological examination, assessing mental state, cranial nerves, upper and lower limbs
The neuromuscular junction
Slides accompanying lecture covering: motor control; the structure of the neuromuscular junction (NMJ); signal transduction at the NMJ; pathophysiology of the NMJ
Thermoregulation
Lecture slides accompanying session on temperature regulation, covering: normal body temperature; temperature regulation and pathological temperature changes
Thermoregulation
The main powerpoint slides used for the thermoregulation lecture given by Prof Parr
Thyroid function
Slides accompanying lecture on thyroid gland and thyroid hormones, hyperthyroidism and hypothyroidism. Enlarged versions of the diagrams are included with the slides.
Transmission of electrical signals by the nervous system
Slides accompanying lecture covering: chemical and electrical gradients; membrane potential; generation of action potentials; transmission along nerves; synaptic and junctional transmission; initiation of action potentials in neurons
Venous return and cardiac output
Slides accompanying lectures on venous return and cardiac output, covering: factors which contribute to preload; measurement of cardiac output; the role of heart rate and stroke volume; Starling's experiments and Starling's law; ventricular failure and heart failure
Virtual patient and respiratory recap
Slides accompanying lecture covering: the architecture of the lung; transport of gases; diagnosis and management of acute respiratory failure
Virtual patient: Acromegaly and thyroid disorder
Case study - Mr and Mrs Roberts with pituitary tumours and hypothyroidism. This case draws on your understanding of endocrine anatomy and physiology. In particular you should be able to integrate the principle of thyroid hormone biosynthesis, hormone action and physiological control.
Vitamins and minerals
Slides accompanying lecture covering: vitamin B12; iron; calcium; vitamin D; copper; zinc
Water regulation
Slides accompanying lecture covering: water absorption in the collecting duct; regulation of plasma osmolarity by the pituitary; urea reabsorption from the collecting duct
Wheeze and asthma
Slides accompanying lecture on the symptoms of breathlessness and wheeze, and associated clinical conditions including asthma, COPD and bronchiolitis