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Understand how to classify the harms of alcohol and other drugs
Slides accompanying lecture describing: viral replication; the mechanism of action of anti-virals and the points at which they have their effect
Slides accompanying lecture on neurotransmitters and the pharmacological management of CNS disorders
Slides accompanying lecture covering: how the body sense pain; the various drug groups involved in treating pain; the mechanism of action and the major adverse effects of these drugs
Handout for BM5 lecture on antiarrhythmic drugs, covering: sodium channel blockers; beta adrenoceptor blockers; potassium channel blockers; calcium channel blockers; adenosine and atropine.
Slides accompanying BM5/6/EU Year 1 lecture on anti-coagulant drugs including warfarin, heparins and direct inhibitors of thrombin and factor X
Slides accompanying lecture covering: types of epilepsy; stages of epilepsy; drugs that suppress focus and prevent spread; drugs that increase inhibitory pathways
Learning outcomes from this lecture: 1. describe indications for and phases of treatment of depressive illness 2. describe the mechanisms of action and properties of commonly used antidepressant drugs 3. summarise the potential benefits and risks of antidepressants 4. describe the indications for mood-stabilising drugs in treating patients with bipolar disorder 5. summarise the potential benefits and risks of mood stabilising drugs
Handout for BM5/6/EU Year 2 lecture by Tony Sampson on malaria and the drugs used in its prevention and treatment.
Slides accompanying BM5/6/EU Year 1 lecture on anti-platelet and thrombolytic drugs
Slides accompanying lecture on drugs used in the treatment of indigestion (dyspepsia), duodenal and stomach ulcers and gastro oesophageal reflux disease (GORD)
Combined slides accompanying lectures on antimicrobials and antibiotic resistance
Antibiotics case presentations, accompanying pharmacology tutorial
Lecture slides accompanying session on antibiotics and antibiotic resistance
Slides accompanying lecture looking at drug strategies in the treatment of depression
A generalised guide to the spectrum over which antimicrobials have their activity
Slides accompanying lecture on antimicrobials covering: antibiotic resistance mechanisms; the targets and drug groups of antimicrobials; the antimicrobial mechanism of action; examples of first line uses for specific drugs
Learning outcomes are to be able to: 1. name classes of drugs used in insomnia and anxiety disorders 2. describe properties of commonly used drugs 3. summarise potential hazards of pharmacological treatments 4.compare pharmacological and psychological treatments
Slides accompanying session on arrhythmias, covering: mechanisms of arrhythmogenesis; consequences of arrhythmias; classification of heart rhythms
An explanation of how to recognise a critically ill patient, and a structured approach to assessing and treating such a patient
Brief description: 1. Psychiatric history of someone with suspected autism, with investigations; 2. How did the concept of Autism/ Asperger's syndrome come about? (background); 3. Diagnosis and Questions to Ask a patient; 4. Conditions Autism may be confused with; 5. Benefits of a diagnosis; 6. What next/ post-diagnosis.
Lecture slides on the autonomic nervous system, covering the anatomy, key features, functions and divisions of the ANS
Lecture slides on the autonomic nervous system, covering acetylcholine (ACh), noradrenaline (NA), and the impact of drugs on the ANS in relation to these.
Lecture slides on the autonomic nervous system, covering adrenoceptors and beta-blockers
Handout for 'Anticoagulants and anti-platelet drugs' lecture to support Tony Sampson's BM4 Year 1 lecture, in versions with 1,2,3 or 6 slides per page.
PRE-ARRIVAL review of the subject of Clinical Pharmacology (What is Pharmacology?) and Introudctory Week Lecture (How doe Drugs Work?) (BM4)
Pharmacology lecture handout on nitrates, beta-blockers, calcium antagonists, plasminogen activators and other drugs in angina and myocardial infarction,
BM5 Y1 lecture on diuretics, ACEI/ARA, digoxin, beta-blockers and other drugs in heart failure
Handout accompanying pharmacology practical looking at whether beta blockers significantly reduce the workload of the heart at rest and during exercise
Slides introducing cardiovascular pharmacology practical exploring the effects of beta-blockers
Question sheet accompanying cardiovascular pharmacology tutorial
Question sheet accompanying the BM5 Y1 clinical calculations lectures
Define dementia, understanding the problem, diagnosis and clinical patterns, management and current therapy
Slides accompanying lecture covering: the function of the kidney; the targets for drug therapy in diuresis; the drugs used in diuresis, their side effects and their first line uses
Slides accompanying tremor symposium, covering: how Parkinson's pathophysiology is modified by drugs; all drugs classes used in Parkinson's; adverse effects and how to counter them
Handout for BM Year 2 lecture on prescribing drugs in pregnancy and lactation.
Lecture by Tony Sampson on prescribing drugs in patients with renal failure (incuding a bit on prescribing in liver disease)
Slides accompanying lecture covering: the aetiology of nausea, vomiting and migraine; the drugs used to treat these; the mechanism of action, side effects and therapeutic uses
Slides accompanying lecture on anti-hypertensive drugs, covering: control of blood pressure and the mechanism of hypertension; consequences of elevated blood pressure; drugs used to reduce blood pressure, their site of action and potential side effects
Slides accompanying session describing the diseases of dyspepsia, GORD and peptic ulcer, and the drugs used to treat these
Slides accompanying contraception symposium, covering the three forms of emergency contraception: copper intrauterine devices; levonorgestrel; ulipristal
This consent form is to be printed out, signed and brought to the practical session to allow the participants to receive eye drops as part of the practical class
Poster presentation linking the physiology, pathology, anatomy and pharmacology of some conditions in the human eye
Handout accompanying pharmacology practical
This tutorial will help you to place a range of drugs covered throughout the GI course
Poster material accompanying gastrointestinal pharmacology practical
Handout for lecture on general anaestheics by Tony Sampson for BM5/6/EU Year 2 students
Slides accompanying contraception symposium, covering the role of oestrogen and progesterone in the menstrual cycle; the mechanism of action of combined and single hormonal methods of contraception and their side effects
Combined slides accompanying IBD symposium, covering the pathology, immunology, pharmacology and clinical aspects of IBD and coeliac disease
Slides accompanying symposium on the pathology, immunology, pharmacology and clinical aspects of inflammatory bowel disease (IBD)
Handout from the lecture on the PSA and SCRIPT given at the introduction to clinical attachments in January of BM5/6 Year 3. Also applicable to Year 4 students, and corresponding years of BM(EU) and BM4.
A reminder about the online PSA in Final Year, including what you need to bring on the day and other information. See also other Medshare resources by searching for PSA.
Contains 1. Overview of the field 2. Case (video) 3. Supporting information for the case 4. Resources for the supporting information a. Sciatica Option Grid b. NICE neuropathic pain pathway c. Startback d. Pain Management Programmes information 5. REsources for introductory lecture a.CMO England report on Pain
An introduction to the principles of drug prescribing, by Riehanh Khan. For BM5/6/EU Year 1 students.
Handout for BM5/6/EU Year 1 lecture by Tony Sampson on lipid-lowering drugs, including statins, fibrates, nicotinic acid and anion-exchange resins
Slides accompanying lecture covering the mechanism of action, pharmacokinetics and uses and methods of administration of local anaesthetics
The aim of this lecture is to enable students: 1. To be able to define major depression and bipolar affective disorder 2. To be able to describe the natural history of mood disorders 3. To be able to describe some of the proposed aetiology of mood disorders 4. To relate the proposed neurobiology of mood disorders to your understanding of neurophysiology
Slides accompanying lecture covering: the history of NSAIDs; roles of prostaglandins; cyclo-oxygenases (COX); adverse effects of NSAIDs; clinical uses of NSAIDs
Information to be used in conjunction with the antihypertensives lecture
Slides accompanying lecture covering: the pathophysiology of pain; opioid receptors; analgesic uses of opioids; non-analgesic effects of opioids; opioid tolerance and dependence
Case and questions for the Y2 Nervous System pharmacology tutorial on pain relief in palliative care.
Combined slides accompanying the peptic ulcer symposium, covering: Helicobacter pylori; Gastro-oesophageal reflux & Barrett’s oesophagus; Dyspepsia, ulcers, reflux and public health; Diagnosis and management of upper GI diseases; Drug treatments
Slides accompanying symposium covering various aspects of GI diseases and their treatment
Handout for Dr Derek Waller's pharmacology lecture in the Peripheral Vascular Disease clinical symposium
Poster describing the types and mechanisms of drug interactions. Used in the PK practical.
Patient cases and questions for the pharmacokinetics practical
Questions for the BM Year 1 Foundations module pharmacology tutorial on drug monitoring
First of four lectures on Pharmacokinetics in Foundations module. Covers administration and absorption of drugs.
Second of four lectures on Pharmacokinetics in Foundations module. Covers drug distribution and metabolism.
Second of two pharmacokinetics lectures by Tony Sampson for BM4 Y1 students
Last of four pharmacokinetics lectures in BM Year 1 Foundations module. Includes answers for clinical calculations.
Slides accompanying symposium on premature labour, discussing the management of preterm labour, the treatments for preventing preterm labour, and their limitations
- Understand how people become physically dependent on alcohol - Know the major neurotransmitters involved - Be able to recognises alcohol withdrawal as a clinical presentation. - Understand the principles of treatment
First of three introductory pharmacology lectures in BM5 Y1 Foundations of Medicine by Prof Sampson
Second of three introductory lectures on basic pharmacology: handout
Third of three introductory lectures on basic pharmacology by Dr Sampson for BM5/6/EU Year 1 students
Revision Lecture (Prof Sampson)from BM Year 1 Semester 2 with key concepts from pharmacology teaching in Locomotor and Cardiopulmonary modules.
Lecture in BM5/6/EU Year 1 by Tony Sampson on the pharmacology of corticosteroids, focusing on cholesterol, glucocorticoids and mineralocorticoids. Sex steroids are covered by a similar lecture in Year 2.
Handout from Tony Sampson for BM4 lecture on 'Pharmacology of Heart Failure'.
Handout for BM4 anti-hypertensive drugs lecture by Tony Sampson. PPT and PDF (6 slide) versions.
Formative assessment of Pharmacology of labour to be completed by students during the Physiology and Pharmacology of Labour lecture
Handout for BM4 lecture by Tony Sampson on drugs for angina and myocardial infarction, and statins.
Slides accompanying lecture describing the main drugs of abuse; the main effects of drugs of abuse on the CNS; dependence and the major pharmacological approaches to treating opioid, nicotine and alcohol dependence
Question sheet accompanying pharmacology tutorial on breast cancer and cytotoxic drugs
Slides accompanying lecture describing: the causes of acute and chronic diarrhoea; the processes involved in constipation; the drugs used to treat diarrhoea and constipation and the mechanism of action of these
Lecture slides accompanying session on the effects of smoking and smoking-related diseases
Handout for BM5/6/EU YEAR 2 lecture focussing mainly on the steroid sex hormones and drugs that modify them, covering: oestrogens; progestogens; oral contraceptive pill (OCP); aromatase inhibitors & anti-oestrogens; testosterone and anti-androgens; anabolic-androgenic steroid drugs.
Slides accompanying pharmacology lecture on the autonomic nervous system (ANS)
Slides accompanying lecture on the pharmacology of the neuromuscular junction (NMJ)
Slides accompanying lecture discussing: the process of labour; control of uterine activity; how the fetus matures in readiness for life after birth; pain relief during labour
Drug side effects task accompanying respiratory pharmacology practical session
A lecture to introduce some of the commoner drugs used clinically to manipulate the cardiovascular system and their mode of action
FAO: Final year students Please find attached a revision guide with some generic tips regarding practical prescribing. The document should be self-explanatory but allows you an opportunity to practice this important skill before you are an FY1. While we are unable to discuss this year’s finals it has commonly been assessed in previous finals, it is the area that many students struggle to master so being familiar with a drug chart is important. It is also an area that every year we receive lots of questions about, this hopefully helps pre-empt them. It has therefore been sent out to all final year students for the last 3 years and we are sending it again this year for the same reasons. It is not however intended to replace any part of your training but to supplement it. If you have questions regarding prescribing please ask the teams in your attachments or during the revision course. We regret the Exams and assessment team, exam & year coordinators will be unable to answer individual queries from students, as stated please address these in your placements and revision course.
BM5 Y1 lecture slides looking at the calculations used in prescribing drugs
psychosis, mood disorders, anxiety, alcohol, autism, ADHD - overview and some questions. Please note, this is not a comprehensive summary, rather a memory aid.
Question sheet accompanying renal pharmacology tutorial on diuretics
Question sheet accompanying tutorial on oral contraceptives and drugs in pregnancy
Slides and notes accompanying webinar, focusing on pharmacology in the management of: stable asthma; asthma attack; stable COPD; exacerbation of COPD
Slides accompanying lecture on respiratory pharmacology, covering: asthma; reliever drugs; preventer drugs (specifically corticosteroids)
Slides accompanying lecture on respiratory pharmacology, covering: preventer drugs; compliance; oral vs inhaled routes; acute and chronic asthma; COPD
Handout accompanying practical session on respiratory pharmacology
Information on SCRIPT software for BM4/BM5/BM6 and BM(EU) students doing clinical modules in their later years, in preparation for the Prescribing Safety Assessment (PSA)
Slides accompanying lecture on aspects of shock, including: causes; pathological changes; physiological mechanisms; inotropic drugs; disorders of acid-base balance; antimicrobial therapy
Slides accompanying respiratory pharmacology practical session, showing skin prick testing for allergy
Classified list of core drugs for Southampton medical students, based on the national student formulary from the clinical section of the BPS, with adaptations. This is an overall guide to the key drugs (and drug groups) prescribed by FY1/FY2 doctors. It does not absolutely define or restrict what is taught and it is subject to updating at any time. Also includes the Top 12 Drug Groups and the Top 40 Individual Drugs. See also the book "The Top 100 Drugs" by Hitchings, Lonsdale, Burrage & Baker (Churchill-Livingstone, 2015).
Summary table listing the action, adverse effects, benefits, indications and contraindications for different forms of steroidal contraception.
Table explaining the function of the main neurotransmitters, the effect of deficit and surplus for each, and how drugs can effect synaptic transmission
A document which provides general information and links to key external websites and learning resources (particularly SCRIPT) to help you prepare for the PSA as you progress through the programme. The SCRIPT map in the appendix aligns the recommended SCRIPT learning modules for Year 3 and then each clinical placement in Years 4 and 5.
This tutorial on an elective surgical procedure brings together a number of drug groups covered in the Nervous & Locomotor courses 1 and 2, including General Anaesthetics, Opiates, Anti-Muscarinics, NMJ blockers, AChEsterase inhibitors, and BDZ sedatives.
Poster from the respiratory pharmacology practical, examining the advantages and disadvantages of oral and inhaled routes for asthma therapy.
Question sheet accompanying pharmacological tutorial
Question sheet for pharmacology tutorial on the neuromuscular junction
Question sheet accompanying pharmacology tutorial on COPD