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6-10 January - Introduction Slides

Prof Paul Roderick

Slides accompanying lecture describing the importance and principles of taking an alcohol and drug history from a patient; detecting alcohol misuse and dependence and the main physical findings in patients with alcohol/drug dependence

Diagram illustrating alcohol related conditions affecting different parts of the body

Understand how to classify the harms of alcohol and other drugs

Slides accompanying lecture on the diagnosis and management of ALS (motor neurone disease/MND)

Slides accompanying lecture on neurotransmitters and the pharmacological management of CNS disorders

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The anatomy and neuroanatomy of swallowing

Slides accompanying lecture covering: types of epilepsy; stages of epilepsy; drugs that suppress focus and prevent spread; drugs that increase inhibitory pathways

Learning outcomes from this lecture: 1. describe indications for and phases of treatment of depressive illness 2. describe the mechanisms of action and properties of commonly used antidepressant drugs 3. summarise the potential benefits and risks of antidepressants 4. describe the indications for mood-stabilising drugs in treating patients with bipolar disorder 5. summarise the potential benefits and risks of mood stabilising drugs

Slides accompanying lecture on drugs used to treat schizophrenia

Slides accompanying immunology lecture on antigen presentation

Slides accompanying session on anxiety disorders, covering: factors involved in the aetiology and maintenance of anxiety disorders; neural correlates of cognitive bias in anxiety; pharmacological and psychological treatment effects

Learning outcomes are to be able to: 1. name classes of drugs used in insomnia and anxiety disorders 2. describe properties of commonly used drugs 3. summarise potential hazards of pharmacological treatments 4.compare pharmacological and psychological treatments

Slides accompanying lecture covering: overview of the orbit; soft tissue; adjacent structures; osteology; fissures and foramina; orbital contents; clinical scenarios

Lecture slides

Powerpoint from attention and perception psychology lecture

Slides accompanying lecture covering: the diagnostic criteria for ADHD; the main differential diagnoses of ADHD; the currently available treatment options

Lecture, Dr Samule Cortese

Brief description: 1. Psychiatric history of someone with suspected autism, with investigations; 2. How did the concept of Autism/ Asperger's syndrome come about? (background); 3. Diagnosis and Questions to Ask a patient; 4. Conditions Autism may be confused with; 5. Benefits of a diagnosis; 6. What next/ post-diagnosis.

Slides accompanying the symposium on relapse of autoimmune disease, describing case studies for Systemic Lupus Erythematosus (SLE)

Case studies accompanying symposium on relapse of autoimmune disease,

Slides accompanying lecture on the anatomy of the autonomic nervous system (ANS)

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Slide deck for the Year 2 B cell Immunology lecture. This slide deck covers: 1. Basic immunology of B-cells 2. Structure, function and generation of antibodies 3. Role of B-cells and antibodies in Multiple Sclerosis 4. B-cell relevant therapeutic interventions for MS

Introduction to Year 2 Immunology Lectures including Semester 1 - Nervous System and Semester 2 - Endocrinology and the Lifecycle

Lecture slides for the lecture on Balance (Jan 2021)

Slides accompanying lecture on bipolar affective disorder (BPAD) covering: epidemiology and aetiology; presentation and diagnosis; challenges and management

Slides accompanying lecture on the arterial supply of blood to the brain, covering the anterior, middle and posterior cerebral arteries, and stroke in relation to each of these

Slides accompanying lecture covering: septic arthritis (SA); osteomyelitis (OM); prosthetic bone and joint infections (PBJI)

Slides accompanying lecture covering: common neoplasms of bone; pathological effects of bone neoplasia; osteosarcoma as a model for principles

Slides accompanying online lecture (BM5 Year 2 Nervous system module MEDI2046)

Slides accompanying lecture covering: brain homeostasis; the structure, function and permeability of the blood brain barrier (BBB); autoregulation of intracranial pressure (ICP); the causes, pathophysiology and management of raised ICP

Lecture on CNS infections; full colour and mainly B&W versions included

Clinical neurology localisation using cases

Clinical neurology localisation using cases

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Slides accompanying symposium on chronic pain, covering: the effects of living with chronic pain; the role of pain management clinics; treatment options available

Slides accompanying symposium on baby with malformations

lecture notes

Slides accompanying symposium on dementia, covering Alzheimer's disease; vascular dementia; dementia with lewy bodies; frontotemporal lobe dementia

Slides accompanying lecture covering: mechanisms driving/triggering chronic degeneration in the mammalian body and how these mechanisms work together to drive complex disease processes; chronic diseases (links with follow-up lectures on specific diseases and clinical cases)

Slides accompanying lectures on the mechanisms common to degenerative diseases such as Alzheimer's Disease and Amyotrophic Lateral Sclerosis; the underlying biology of degenerative diseases, and exploring age-related macular degeneration (AMD) in detail.

Clinical neurology localisation

Slides accompanying lecture covering: the A-B-C model; thinking errors; survival mode vs competency mode; the stressor-response chain

Slides accompanying lecture on consciousness, covering: the medical definition and anatomy of consciousness and sleep; the pathological basis of impaired consciousness; the Glasgow Coma Scale; the criteria for brain death

UK national CJD surveillance data up to November 2019

Define dementia, understanding the problem, diagnosis and clinical patterns, management and current therapy

Slides accompanying lecture on depression covering: the aetiology, presentation and management of depression; the bio-psycho-social model; the role of the psychiatrist and the multidisciplinary mental health teams

Slides accompanying session examining some of the key current controversies and complexities surrounding depression and considering the relevance of these controversies & complexities for doctors and patients

Slides accompanying symposium on baby with malformations, covering the embryological development of the nervous system, and related clinical fetal malformations

Slides accompanying symposium on relapse of autoimmune disease

2-page history-based flow-chart for diagnosing dizziness

Slides accompanying symposium exploring key aspects of domestic abuse relevant to medicine

Slides accompanying tremor symposium, covering: how Parkinson's pathophysiology is modified by drugs; all drugs classes used in Parkinson's; adverse effects and how to counter them

Slides accompanying lecture covering: the aetiology of nausea, vomiting and migraine; the drugs used to treat these; the mechanism of action, side effects and therapeutic uses

Two-part illustrated chart describing embryonic development from 4 days to 55 days

Slides accompanying symposium on stroke, discussing the occurrence of stroke in the population, the risk factors for stroke and strategies to reduce deaths from stroke

Slides accompanying lecture on epilepsy, covering: classification and diagnosis; medical and surgical managemenr of epilepsy; common problems in epilepsy

Slides accompanying lecture covering: recognising and classifying seizures; definition and causes of epilepsy; examination and management

Slides accompanying lecture covering: the social and psychosocial effects of substance misuse; the physical harms of substance misuse; the various ways users may present; the complications of commonly used drugs

This consent form is to be printed out, signed and brought to the practical session to allow the participants to receive eye drops as part of the practical class

Slides accompanying pharmacology practical

Poster presentation linking the physiology, pathology, anatomy and pharmacology of some conditions in the human eye

Handout accompanying pharmacology practical

Slides accompanying lecture on foetal alcohol syndrome, covering: effects of alcohol on a pregnancy; basic embryology; Fetal Alcohol Syndrome; epidemiological data on alcohol in pregnancy

Two-part illustrated chart describing foetal development from 7½ weeks onwards

Slides accompanying lecture covering: the topographical organisation of the brain; the key regions of the cerebral cortex and their function; the components of the basal ganglia and its function

Slides accompanying lecture covering: the hippocampus; the thalamus and hypothalamus; the brainstem; the cerebellum; the limbic system

First of two sets of slides, with labelled images showing the anatomy of the brain

Second of two sets of slides, with labelled images showing the anatomy of the brain, including the brainstem, hippocampus and cerebellum

Handout for lecture on general anaestheics by Tony Sampson for BM5/6/EU Year 2 students

Slides accompanying lectyure covering: the different forms of chromosomal and molecular genetic abnormality; the major clinical manifestations and management issues of neurogenetic diseases

A doctor describes her experience of alcoholism and the AA

Slides covering: principle types of lesions in head injury; extradural, subdural and intracerebral haematoma; surface contusions and brain lacerations; diffuse axonal injury (DAI); intracranial pressure (ICP)

Slides accompanying symposium on traumatic brain injury, describing the epidemiology of head injury and key prevention strategies

Slides accompanying lecture covering primary headaches including: tension headache, migraine and cluster headache; and secondary headaches including: raised intracranical pressure; vascular headaches; meningitis or encephalitis; giant cell arteritis

Slides accompanying lecture introducing the 'alpha' Herpes viruses and the concept of latency, concentrating on infections of the CNS

Notes accompanying lecture introducing the 'alpha' Herpes viruses and the concept of latency, concentrating on infections of the CNS

Slides accompanying lecture covering: structure and organisation of the cortex and lateralisation of function; lesions of the Parietal Association Cortex, Frontal Association Cortex, Cortical Centres for Language and Temporal Association Cortex

Slides accompanying lecture introducing prion diseases

Notes accompanying lecture introducing human prion diseases

Slides accompanying symposium on traumatic brain injury

Appreciate the epidemiology of alcohol use and misuse Know how to calculate units of alcohol Have some tools up your sleeve to help with screening for alcohol use disorders and assessment of alcohol withdrawal

Slides accompanying symposium on relapse of autoimmune disease

Slides accompanying lecture providing a reminder of basic immunology and introducing the course format and lecture content for the Year 2 immunology lecture series

Slides accompanying lecture covering: Antibody/Immunoglobulin (Ig) structure; pathways of B-cell differentiation or maturation; B-cell effector functions; B-cell disease associations: RA

Lecture slides from Innate Immunity Lecture

Slides accompanying lecture on innate immunity

Slides accompanying lecture covering: types, effects and clinical signs of space occupying lesions; causes, measurement and treatment of raised intracranial pressure (ICP)

Introduces a System to management Pain successfully

This gives an overview of the area, core concepts that students need to be aware of and an understanding of how the week has been constructed to ensure students understand the mutifactorial nature of this complex clincal problem

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Slides accompanying introductory lecture to the NLM2 module

Contains 1. Overview of the field 2. Case (video) 3. Supporting information for the case 4. Resources for the supporting information a. Sciatica Option Grid b. NICE neuropathic pain pathway c. Startback d. Pain Management Programmes information 5. REsources for introductory lecture a.CMO England report on Pain

Slides accompanying symposium on relapse of autoimmune disease

Slides accompanying lecture covering: the key principles of brain organisation; neurons; epigenetics; key terminology in neuroanatomy

Slides accompanying lecture covering: the visual pathway from retina to V1; visual defects associated with lesions along this pathway; pathways from V1 to other cortical regions

Lecture introducing the main concepts of ionotropic receptors in the central nervous system

Slides accompanying lecture describing key excitatory and inhibitory ionotropic receptors

Slides accompanying lecture covering the mechanism of action, pharmacokinetics and uses and methods of administration of local anaesthetics

Clinical neurology localisation - key features

Slides from Dr Richard Marigold

Slides accompanying lecture covering: ischaemic neurodegeneration; the ischaemic core and ischaemic penumbra; clinical treatment for stroke patients

Notes accompanying lecture on bacterial meningitis covering meningococcal infection, its pathogenesis, treatment and prevention

Slides accompanying lecture describing the basic biochemistry of alcohol metabolism

The aim of this lecture is to enable students: 1. To be able to define major depression and bipolar affective disorder 2. To be able to describe the natural history of mood disorders 3. To be able to describe some of the proposed aetiology of mood disorders 4. To relate the proposed neurobiology of mood disorders to your understanding of neurophysiology

Slides accompanying lecture on motivational interviewing, covering: general principles of motivational interviewing; key skills; Prochaska and DiClemente's Stages of Change module

Slides accompanying lecture covering: the role of reflexes in control of movement and the systems that integrate them into a co-ordinated motor control system; the central mechanisms involved in the generation of voluntary movements

Slides accompanying lecture covering the corticospinal tract; the corticobulbar tract; and the vestibulospinal, reticulospinal, tectospinal and rebrospinal tracts

Slides accompanying lecture covering: the corticobulbar pathway; bilateral and contralateral innervation; the facial nerve and hypoglossal nerve

Slides accompanying symposium on relapse of autoimmune disease

Slides accompanying spinal cord lecture covering compressive (surgical) and non-compressive (medical) myelopathies

Cases to be studied ahead of the lecture on myelopathies

Preparatory material for the online Nervous System Pathology tutorial on Thursday 12 November (on Blackboard Collaborate). The version with answers has now been uploaded.

Preparatory material for the online Nervous System Pathology tutorial on Thursday 19 November (on Blackboard Collaborate). The version with answers has now been uploaded.

Preparatory material for the online Nervous System Pathology tutorial on Thursday 3 December (on Blackboard Collaborate). The version with answers has now been uploaded.

Slides accompanying neuroanatomy workshop, describing a range of cases

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Slides accompanying lecture exploring the role of neuroplasticity in injury outcomes and daily living

Slides accompanying lecture introducing the nutritional considerations of excessive alcohol consumption and alcoholism

Slides accompanying lecture covering: the pathophysiology of pain; opioid receptors; analgesic uses of opioids; non-analgesic effects of opioids; opioid tolerance and dependence

To accompany the lecture

Case and questions for the Y2 Nervous System pharmacology tutorial on pain relief in palliative care.

Slides accompanying tremor symposium, covering: common movement disorders; clinical features of Parkinson's disease (iPD); diseases the can be confused with iPD; treatments for iPD

Slides accompanying symposium on dementia, describing the pathology of vascular dementia, Alzheimer's disease and other neurodegenerative disorders

Slides describing the major pathological processes causing stroke, covering: cerebral infarction; intracerebral haemorrhage; subarachnoid haemorrhage

Patient quotes from video, describing experiences of HIV, Parkinson's disease, rheumatoid arthritis, epilepsy, coronary heart disease and cancer

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- Understand how people become physically dependent on alcohol - Know the major neurotransmitters involved - Be able to recognises alcohol withdrawal as a clinical presentation. - Understand the principles of treatment

Slides accompanying lecture describing the main drugs of abuse; the main effects of drugs of abuse on the CNS; dependence and the major pharmacological approaches to treating opioid, nicotine and alcohol dependence

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Slides accompanying lecture covering the peripheral and central mechanisms involved in the detection, transmission and response to pain

Test your knowledge onPain Management

psychosis, mood disorders, anxiety, alcohol, autism, ADHD - overview and some questions. Please note, this is not a comprehensive summary, rather a memory aid.

Slides accompanying lecture covering: the ways in which a chronic condition impacts on a patient's life; adjustment to a chronic condition; psychological factors that help or hinder adjustment; psychological approaches that can be used to reduce distress and improve quality of life for people with chronic conditions

Lecture slides

Introduction to psychological aspects of additive behaviour

An introduction to the psychotic illnesses Their aetiology, presentation, and the stigma surrounding them

Lecture about Psychosis symptoms and case studies

Slides accompanying lecture describing: the health consequences of acute and chronic alcohol consumption; current patterns of consumption in the UK; strategies aimed at alcohol harm reduction

Slides accompanying lecture on stress and building resilience

Slides accompanying lecture covering the major and minor salivary glands, the nasal cavity and paranasal sinuses

Overview of history, presentation and treatment

Lecture slides from Georgina Burke 2019

Slides accompanying lecture exploring neurology cases, covering: descending motor pathways; ascending sensory pathways; autonomic nervous system; history taking and examination; upper and lower motor neurone lesions

Slides accompanying the lecture given by Dr Aravinthan Varatharaj 2019

Slides accompanying lecture covering the spinothalamic tract and the dorsal column/medial lemniscal tract

Slides accompanying lecture covering the trigeminothalamic tract and the spinocerebellar tract

Slides accompanying radiology lecture covering: imaging methods; the anatomy of the skull and cervical spine; injury, tumours and congenital abnormalities

Slides accompanying lecture covering: how we define, understand and address addiction; the social harms of drugs including alcohol; whether drugs should be decriminalised/legalised; the consequences of this debate for doctors

Slides accompanying lecture on speech and language problems, covering: dysphonia; dysarthria; dysphasia; conduction aphasia; transcortical sensory aphasia; progressive aphasias

Slides by Dr Sam Hall

Slides accompanying lecture on spinal injuries, including: spinal cord injuries; upper cervical spine injuries; subaxial fractures

Slides accompanying symposium on stroke, describing the causes and types of stroke

Material to accompany stroke tutorial (including complete answers)

Slides accompanying wrap-up session for stroke case

Slides accompanying lecture covering: structure of CNS synapses; model organisms for studying synaptic plasticity; long-term potentiation; long-term depression

Slides accompanying lecture covering: the basic concepts underlying synaptic transmission; how synaptic transmission may be regulated; the role of synaptic transmission in the CNS

The powerpoint slides from the Wounded Healer Session

Slides accompanying lecture describing the anatomy of the brainstem; cranial nerve functions and brainstem reflexes; corneal and pupillary light reflexes; the medial longitudinal fasciculus (MLF)

First of two sets of slides accompanying lecture on the ear, covering hearing and conditions causing hearing loss

Second of two sets of slides accompanying lecture on the ear, covering balance and the vestibular disorders causing vertigo and imbalance

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Slides describing how to carry out a neurological examination, assessing mental state, cranial nerves, upper and lower limbs

This tutorial on an elective surgical procedure brings together a number of drug groups covered in the Nervous & Locomotor courses 1 and 2, including General Anaesthetics, Opiates, Anti-Muscarinics, NMJ blockers, AChEsterase inhibitors, and BDZ sedatives.

Slides accompanying lecture on raised intracranial pressure (ICP) and space occupying lesions (SOL) using brain tumours as an example

Slides accompanying tremor symposium, covering: the parts of the brain that form the basal ganglia; the motor loop; how basal ganglia nuclei influence motor activity; Parkinson's disease

Question sheet accompanying pharmacological tutorial

Question sheet accompanying pharmacology tutorial

Slides accompanying session exploring the effects and treatment of substance misuse, particularly among socially excluded populations

Case study - baby Gabriel with head and neck malformations

Case study - John Regan with chronic pain

Lecture about importance of sleep